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July 1, 2008

Source: Daily Mail

Scientists have shown that the drink cancels out some harmful substances produced by the meat in the stomach. The chemicals – released during the digestion of fat – are linked to a host of ills, including cancer, hardening of the arteries, diabetes and Parkinson’s disease.

January 14, 2008

Source: Sirtris Pharmaceuticals

A compound found in red wine may eventually treat age-related diseases such as obesity and diabetes.

A Massachusetts-based drug company, Sirtris Pharmaceuticals, has found that a reformulated version of resveratrol, a compound found in red wine, improved the body’s ability to break down sugar – and prevented mice from becoming obese. In trials Sirtris’s SRT501 drug was showed that those taking resveratrol improved their score on an oral glucose tolerance test, which measures the body’s ability to break down and use sugar, a fundamental problem for diabetics.

November 28, 2007

Source: The Daily Telegraph http://www.telegraph.co.uk/science/science-news/3316401/Red-wine-may-provide-cure-for-diabetes.html

Millions of people with adult diabetes could one day be treated with a drug based on the healthy ingredient of red wine which could even help prevent other diseases linked with old age.

The new class of drugs, which will be tested on patients next year in Europe or the US mimics the effects of a reduced-calorie diet, which is known to extend the lifespan of a wide range of creatures, from worms to mice and monkeys.

The problem with red wine is that earlier animal research suggested that around 1000 glasses would have to be consumed each day to take enough resveratrol to reduce the impact of a high fat diet, increase stamina two fold and significantly extend lifespan.

Now new compounds have been developed that are roughly 1,000 times more potent than resveratrol and are also 1,000 times better at staving off the development of type 2 diabetes, report researchers led by Christoph Westphal of the company Sirtris Pharmaceuticals, Cambridge, and David Sinclair of Harvard Medical School, in today’s Nature.

December 13, 2002

Source: New Scientist

Researchers in France’s Languedoc region have created a white wine with nearly all the health benefits of red, the New Scientist reports. And it could signal the start of a new generation of wines that help tackle specific medical conditions.

Paradoxe Blanc, a Vins de Pays d’Oc Chardonnay, takes its name from the so-called ‘French Paradox’, a phenomenon whereby the French, who eat more saturated fat than their neighbours in the rest of Europe, suffer lower rates of heart attack and cardiovascular disease.

Many now believe it’s the nation’s habit of drinking red wine with meals that gives protection, thanks in part to red wine’s high polyphenol content. Red wine’s antioxidant polyphenols have been found to block production of a natural chemical – endothelin-1 – which causes blood vessels to constrict, so increasing blood pressure and risk of heart problems.

But it is people with diabetes who are most likely to benefit from the new creation, says Dr Pierre-Louis Teissedre, who led the original research at the University of Montpellier.

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